Many individuals with mid-cervical spinal cord injuries (SCI) rely on wrist supports or orthotics in order to keep their wrists stabilized to grant them more functional ability. However commercially-available wrist supports principally provide support to perform limited activities of daily living (ADL) with cuff attachments. We developed and tested a motor-activated wrist orthotic system, the WristSense, which uses a two-tier gesture recognition approach to assist individuals with SCIs to perform a larger range of ADL. The WristSense was used as a PowerPoint presenter remote control to allow individuals with SCI to present without much hassle. WristSense can be adapted by adding a variety of actuated tools to expand the ability of wearers to perform various ADL.